Taking 50 mg twice daily reduced mental fatigue and improved subjective well-being in students during an examination period. Taking mg twice daily for 7 days reduced fatigue, but not stress, in university students. In night shift physicians, mg daily reduced feelings of fatigue and improved mental performance.
In military cadets, a single dose of mg after 24 hours without sleep improved tests of mental processing and short-term memory. In patients with stress-related fatigue, mg daily for 28 days decreased symptoms of fatigue and increased attention.
However, there were no improvements in quality-of-life or symptoms of depression. While some evidence suggests that the herb may be helpful for enhancing physical performance and alleviating mental fatigue, methodological flaws limit accurate assessment of effectiveness. More research is needed to determine true benefits of R. Rhodiola extract SHR-5 mg once or twice daily significantly reduced symptoms of mild-to-moderate depression after 6 weeks of treatment and decreased overall depressive symptoms, emotional instability, insomnia, and somatization.
However, due to the inadequacy of studies, no definitive dosage recommendations can be made at this time. Rhodiola typically has few or no side effects, unlike traditional stimulants that impair sleep, cause rebound sleepiness and have addiction, tolerance and abuse potential. Although no contraindications with other herbal or prescription medications have been identified, it is important to consider that Rhodiola may have an additive effect with other substances that have stimulant properties.
The proposed mechanisms underlying the potential protective effects of salidroside involvement include the regulation of oxidative stress response, inflammation, apoptosis, hypothalamus-pituitary-adrenal axis, neurotransmission, neural regeneration, and the cholinergic system.
While Rhodiola appears to have multiple benefits which are likely to reflect more than one mechanism of action, a recent study shows Rhodiola to have inhibitory effects on the monoamine oxidases MAO-A and MAO-B.
Monoamine oxidase MAO -A regulates the metabolic breakdown of the monamines adrenaline, noradrenaline and serotonin in the central nervous system and peripheral tissues. MAO-A inhibitors have proven to be effective in the pharmacological treatment of depression.
MAO-B is an enzyme involved in the breakdown of dopamine, thus Rhodiola may raise dopamine levels. Rhodiola is also a component of SynaptaGenX previously marketed as Synaptamine , a medical food use in the management of Reward Deficiency Syndrome which is associated with suboptimal dopamine levels in the reward centers of the brain.
Although many preclinical studies have demonstrated clear neuroprotective effects of salidroside, none of the salidroside preparations have so far entered medical clinical trials, and there has been no definitive clinical evidence to confirm the efficacy of salidroside.
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Table of contents. What is rhodiola? Is Rhodiola rosea water-soluble or fat-soluble? Where can rhodiola be found naturally? Common sources of rhodiola: The only known source of salidroside is the rhodiola flower, and the active compounds in rhodiola are usually prepared in oral supplement form. What is the recommended daily value for rhodiola? Can you absorb enough rhodiola from food?
Why is Rhodiola rosea necessary for your body? Functions of rhodiola Potential adaptogenic benefits: Researchers have identified rhodiola as a potential adaptogen, which means that this natural substance may help you adapt to stress in a healthy way.
Potential physical and mental performance benefits: Research indicates that taking rhodiola extract may improve both physical and cognitive performance by reducing fatigue and enhancing concentration. Potential mood benefits: Studies suggest that rhodiola may be able to help with both anxiety and depression, which means that this plant extract may generally improve your mood.
Potential eating disorder benefits: Research indicates that rhodiola may help prevent stress-eating and binge-eating, which are eating disorders that can contribute to serious conditions like anorexia and bulimia. Other potential benefits: Recent research indicates that rhodiola may also exert potent anti-inflammatory and neuroprotective benefits.
When should you take rhodiola? How long do you need to take rhodiola to start experiencing its benefits? How long does rhodiola stay in your body after you take it? Is Rhodiola rosea an antioxidant? Can you overdose on rhodiola? In vitro and animal research shows that rhodiola can decrease blood pressure by inhibiting angiotensin-converting enzyme.
Rhodiola may benefit people with milder stress-related symptoms or disorders. Interested in learning whether rhodiola is right for you? No waiting in line or uncomfortable swabs. Is Rhodiola Good for Anxiety? July, 20 Vitamins. Start The Assessment. Inline Feedbacks. Share this article 3 4. Read more about Vitamins July, 20 Vitamins. July, 21 Vitamins. August, 28 Vitamins. Feel better. Look better. Live better. Vitagene proudly accepts:. Blog Blog Success Stories.
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